I often suggest that satire is a dangerous double edged sword and not a good primary vehicle for positive change. Part of your audience will understand it's satire, but a significant part maybe even a majority, might take is as genuine or worse come to embrace/support the satirized.
I believe we ask and expect too much of satire which relies heavily on hypocrisy and shame, two concepts that no longer carry the same weight.
Examples: South Park, The Colbert Report, SNL, The Onion