"It's outside the environment."
> has considered a high-thrust nuclear
Of course we have. Always start at NTRS: https://ntrs.nasa.gov/citations/19690000736
> Certainly sci-fi has!
Our Solar system is a gravitational well that tends to put things in solar orbit. You really want the waste products to leave the solar system, which isn't terribly difficult, or you want them to land on the sun itself, which is exceptionally difficult.