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Virtualization (Hyper-V) can also be enabled, without enabling the Hyper-V Manager or WSL2 Windows Components, if the "Core Isolation" security setting is enabled.

The biggest telltale for me is that hyper-v and wsl breaks anything that uses the ethernet mac as part of a host-id, and mobaxterm is unable to run it's X11 server because something about the hyper-v virtual ethernet screws it

Or enabled the security features anyone should be running in first place, thus yeah since Windows 11, it is for all practical purposes.

Same applies to XBox Windows flavour.

IOMMU is my borrow checker