At that point, if you're making the two calls how is LISP's behavior any more ergonomic than Scheme. I'm not saying it's not possible, I just don't see it.
Can you show code between the two and how one is much worse than the other?
Even when we have a heterogeneous list in Lisp, like one that can have symbols, numbers, strings or widgets, we can almost always exclude nil as a matter of design, and thus cheerfully use the simpler code.
We cannot exclude nil when a list contains Boolean values, because nil is our false.
We also cannot exclude it when it contains lists, because nil is our empty list.
The beauty is that in many situations, we can arrange not to have to care about the distinction between "item is missing" and "item is false" and "item is an empty list", and then we can write terser code.
When you see such terse code from another programmer, you know instinctively what the deal is with how they are treating nil before even looking at any documentation or test cases.
for example a useful datatype is an association list. (setq x ((a . 1) (b . 2) (c . nil))) you can query it by calling (assoc 'a x) which is going to give you back a cons cell (a . 1) in this case. now the presence or absence of this cell indicates the association. if you want to know explicitly that C is nil, then you have an option to, and it's similar in function call counts to Scheme. if you don't care though about the distinction you can do (cdr (assoc 'a x)) which is going to give you 1. doing (cdr (assoc 'foo x)) will give you nil without erroring out. it's a pretty common pattern.
in case of established data types like association list, you will probably have a library of useful functions already defined, like you can write your own getassoc function that hides the above. you can also return multiple values from getassoc the same way as gethash does the first value being the value, and the second value being whether or not there's a corresponding cons cell.
but when you define your own adhoc cons cell based structures, you don't have the benefit of predefined functions. so let's say you have an association list of symbols to cons cells (setq x ((a . (foo . 1)) (b . (bar . 2)) (c . nil))). if I want to get foo out of that list, I'll say (cadr (assoc x 'a)) which will return foo. doing (cadr (assoc x 'c)) or (cadr (assoc x 'missing)) will both return nil. these later manipulations require extensive scaffolding in Scheme.