You absolutely do. Many coworkers will bug you to ask instead of doing their own research, bug you to chitchat, etc.

They can always book time with you, send an email/IM, etc if there's something they can't resolve on their own.

You have your own deliverables and being interrupted every 10 minutes with inane questions that a web search or a look at the internal wiki/KB would have resolved is not a productive use of anyone's time.

Also, forcing them to wait produces better quality, better researched questions as hopefully they should make some attempt to resolve things on their own.