I wonder if they will. I can't imagine anything trackpoint-like -- too expensive -- but it's not impossible they'll put a trackpad in.
The Pi 400 is small because it's meant to be aimed at the young. But young children are good with clicking buttons and poor with fine dexterity; they will likely do better with mice.
A clip-on trackpad to go alongside it would be nice, though.
I'm not really the target market but I am hoping a Pi 500 will tick all the right boxes to use as a cheap computer in a space-constrained workshop.