Centralized blockchain ledgers for immutable data storage is immensely useful to detect silent corruption or malicious data tampering for specialized use-cases (backup & restoration with air-gapped storage processes are required to assure high-confidence data integrity to correct such data problems).
GPU, server systems, and network access are so damn cheap and impressive with incremental advances that the killer apps challenges now are sanely management, planning, and cross-cutting concerns like emulation, resource allocation, configuration management, monitoring, security, and effective discovery and implementation of appropriate and benchmarked solution(s).
The application of LLMs yet aren't to the point of complete silicon & PCB design, application development, or systems management assuring a level of correctness using iterative feedback, but probably will approach something useful over time. Perhaps in 50 years, all living humans will lack the understanding of what software will have "eaten" in certain areas if engineers allow it and corporations optimize for it.