The currently used R32 is equivalent to 675x the CO2, so a typical AC unit will have several tonne equivalents of it inside.
That's still an upgrade over its predecessor - R410a, for which the same figure was 2088x.
Heat pumps have the same problem, which is why the recently deployed 33MW district heating heat pump in Helsinki uses CO2 as a refrigerant:
https://www.man-es.com/company/press-releases/press-details/...