Not until someone implements the handling of such in XLSX import. Excel needs a cloud connection to run Python and there are apparently some homegrown functions like xl(), so it probably would not be straightforward:
Why in gods green earth would you want a cloud connection to run a Python script on your computer when you canr run python locally since day 1 of Python ?
So these files wont run if you are offline ?
Maybe Microsoft thinks it's a good solution to security concerns, if the code is run in their sandbox.