You can accept the risk that your savings will dwindle to zero; you can in fact stipulate that the chances of that happening are 99.9%. You can tell yourself, probably truthfully, that the life cost of zeroing out your savings is minimal, because you will almost certainly be as (or maybe more) employable when you finish your venture.
What you will not ever get back from a failed venture is the time you sunk into it. You will, I am fairly certain, come to realize that lost time is the worst kind of loss; your time is not only effectively money, but also opportunity.
Pick what you're working on carefully. Every startup founder in the history of startup founders has told themselves, "even if this thing fails, it will be a great experience". As someone who has failed at a startup: failure is indeed educational. But at 2-3 years of the most productive, least encumbered years of your life, the tuition is expensive; it's a rip-off. Don't buy it.
† Ironically, Yoskovitz appears to be exactly my age.