I use that ALL the time. I can navigate straight to any issue by typing a URL. I can switch to the “actions” view for a repo by adding /actions. I can see the file I’m looking at in a branch by editing the URL and swapping “main” for the branch name.
All available via the UI as well, but I interact with GitHub so often that the tiny efficiency boost I get from navigating by URLs really starts to add up.
I also trust them not to break links, based on their track record. My notes and blog posts and even my source code are full of links to issues or code snippets on GitHub.