-- Immunity to prion diseasy by epigenetically silencing the prion gene,
-- Cure (almost) all cancers
-- life long HIV AIDS immunity with 1 vaccination (based on a modified virus)
-- Extend life by a factor 2 (if I'm not mistaking)
-- Make them light up in the dark with a human ear growing on their back (this one is decades old already).
And all of the above is without considering the AGI singularity.
Human immunity is really not that far away. Depending on how AGI will respond to us we will soon either be wiped out or be immortal IMO.