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> one of the first lessons you learn on day one is how one-factor-at-a-time testing is one of the most inefficient ways you can test something

Isn't that just called unit testing?

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Completely unrelated concept: unit testing is part of a regression testing framework while OFAT is a (almost always suboptimal) test strategy for designed experiments.

See:

https://en.m.wikipedia.org/wiki/One-factor-at-a-time_method

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