PS. One thing I have always found fascinating - obvious as it might be - is that paper (and paper in large, sufficiently cheap industrial quantities) was a prerequisite for the printing press "revolution" to take place ...
What you point out is fascinating, and probably right ...
PS. I am wondering if "any sufficiently popular" book might not have done the trick, beyond just "sacred" texts - one of the many knightly tales than making the round, for example.-
The people building DIY electric cars in the 90s were using lead acid batteries charged with very slow trickle chargers, not because they were ignorant, they just didn't have access to the better technology we have now. People 50 years with some sort of cold fusion battery from now will look at our crude electric cars running on chemical batteries and laugh.
The demand was there as well, Romans imported papyrus from their warmer colonies and went through a lot of it. They also used parchment, but it was expensive, a lot of writing ended up being done on reusable wax tablets.
Paper was invented when the Western Roman Empire was still extant, and while the Chinese could fairly be said to have had a technological edge over the Romans at the time, it's dubious that said edge played a direct role in the invention. It just, didn't happen.
I agree with the general sentiment, and wouldn't call paper "fairly modern" either. But given the topic, it seemed worth a mention.
ADDED: The Romans did apparently have some knowledge of antibiotics without presumably understanding the mechanisms or refining them. Per Wikipedia and other sources: "Antibiotics have been used since ancient times. Many civilizations used topical application of moldy bread, with many references to its beneficial effects arising from ancient Egypt, Nubia, China, Serbia, Greece, and Rome."
> ADDED: The Romans did apparently have some knowledge of antibiotics
Fascinating. Worth looking into.-
Sometimes, all it took was one person noticing something (midwives who wash their hands post partum tend to have better outcomes, farmers near cows get less sick, or not at all ...)
... but, you raise another good point: First principles, the search for the facts. Benefits at scale come with, consistently, wanting to go from observation, to general principles, to particular application, to mass application ...
... and, maybe, it took rational thought and the scientific method to get there.-