The issue is Defender in sync mode/other AV/other file system filters.
DevDrive as noted by default uses an async scanning technique as well as ReFS. ReFS will suffer the exact same performance issues with Defender (or other AV/other file system filters) doing its thing when running in sync mode, which it does by default for ReFS-formatted drives in Windows Server.
https://gregoryszorc.com/blog/2021/04/06/surprisingly-slow/
https://news.ycombinator.com/item?id=26737521
> Except for CloseHandle(). These calls were often taking 1-10+ milliseconds to complete.
> While I didn't realize it at the time, the cause for this was/is Windows Defender. Windows Defender (and other anti-virus / scanning software) typically work on Windows by installing what's called a filesystem filter driver.
This doesn't take away from your point that _it is slow_, but the reasons are not due to the file system in use.