Depleted uranium is not explosive: You will not have an explosion like a nuclear bomb.
A nuclear engineer can probably explain this better.
My understanding is that depleted uranium is a highly toxic substance, so we wouldn't want it to leech into soil / groundwater. I also doubt meltdowns are a substantial risk because the fuel pellets would have to fall / land in a way that they are concentrated together.
Funny anecdote: Two years ago I took my family on vacation, and I happened to be near a pumped hydro storage plant that was built to balance an early reactor. I couldn't find it, and when I turned around, I looked out the windshield, and across the river was a bunch of nuclear waste in dry storage: https://www.google.com/maps/place/Yankee+Atomic+Electric+Co/...
I wouldn't have even known what it was if I hadn't gone looking for it on Google Maps a few years prior.
Getting back to the point, if an asteroid hit the dry storage that I mapped above, I doubt there would be an explosion. The Deerfield river would probably become very toxic, but I wouldn't call it an extension event.