Great followup and details. Your introspection sounds like you're on the right path for evolving and making progress. There is no silver bullet here (at least in my own experience).

Your three priorities (if I understood correctly), sound like your health, relationship, and independent business. This really does seem like a good track. In fact, having such clarity of priorities puts you ahead of many people. The only thing I don't see is maybe having a vision of the environment in which you pursue these priorities (home, living area, weather, etc).

I encourage you to consider specific short and medium term goals within those three areas. Maybe you can help draw out several purposes that adjust your mental framing.

As a small example, the hot topic of the children. I don't perceive anyone saying you should rush out and have a child tomorrow. Instead, adapting to your situation, maybe there are some specific family goals for the next few years.

Then, on the business side, maybe there are some specific goals for the next 1, 3, and 6 months. This might also need some goals about when to cut bait and try some different business ideas.

When I'm in the worst malaise, it's often when I have vague big picture aims without shorter term goals. Purpose is multi-faceted.

Thanks for sharing your journey. It's helpful for me to think and write about these topics, so I appreciate the prompt and hope I've helped your pursuit in a small way.