While I generally prefer the classic keyshapes, my main problem with the new Thinkpad keyboards is the removed row.
Instead of the Insert/Delete/Home/End/PgUp/PgDown key block in the upper right corner, the keys are put into the function key row. This also means that the gaps between F4&F5 and F8&F9 are removed. They also removed the menu key and replaced it with Print for some reason.
With the old Thinkpads, you could just pick them up and start typing without having to learn too many idiosyncrasies of the laptop keymapping. This is not the case anymore. When you work both on a laptop and a regular keyboard, this gets really painful.