OP here — yes, I absolutely agree!
The "hard" work of creating the Workers technology and service is useless if they don't do the arguably easier (but more tedious) work of getting the ecosystem to play well with Workers. This means making a list of the Top 1000 most popular packages on Node.js, and finding ways to make as many of them work on Workers as possible. For the ones where it's too hard/impossible, there should be *well-documented* alternatives.