Yes, mostly. That is, if a Photoshop plugin is well-behaved and doesn't make use of undocumented aspects, it's pretty much going to work.

https://peterthenaturephotographer.com/process/affinity-phot...

https://affinity.help/photo/en-US.lproj/index.html?page=page...

If you mean Photoshop>Photo plugins. Affinity doesnt otherwise have any third party plugins or scripting. Unfortunately.

"It depends." Some work, some do not. Just try.