I dont get it. The first hit there says it is a rare disorder due to cancer; so this is already not the more common case. Second it is still due to the presence although not local of the tumor. If you destroy the tumor you may have a chance of resolving the condition.

I am aware of necrosis. You need to either completely break down the cell or remove the material. Radiation of course does not do this but surgery of course does.

My appeal to you would be to allow more disruption in this space. Software and Hardware are (mostly) unregulated which allowed for the explosion of progress.