I switched from GMail to Fastmail about a year ago, but ever since my Inbox is just filled with lots of spam. I tried writing email filters, and have about 50 now, but it is just not cutting it.
And also those promotional mails that I don't want to mark as "spam" but still shouldn't end up in my Inbox ... they drive me nuts.
Since I started using Fastmail, my main means of communication is shifting away from e-mail, which is sad.