Edit:
https://www.fractyl.com/fractyl-health-demonstrates-signific...
That's fascinating.
Perennial light sleeper, couldn't drink caffeine either due to extreme long half life and sleep issues. On it, fall asleep at night like a "normal" person for the first time. Able to drink coffee too. I chalked that up to the fact it does have a bit of a drowsiness effect, but... then I noticed I was just having a bit less back pain. Noticed my tingling in feet and muscle fasciculation was down.
I've been on and off it now ever since, but I take lower doses/breaks since I don't need it for weight. But I was getting "attacks" of inflammation every ~6 months, since doing it for 1.5 years not a single attack (knock on wood).
My thought there is - yes fasting is great for a lot of things and maybe helped, but I can't help but think it's other effect. I've tried a lot of things, even other peptides that supposedly work and had 0 effects across hundreds of supplements. This stuff had huge effects.
The friend I can't speak to much, simply that they told me they started it and without my prompting told me a couple months later about the allergy thing.
I wonder how that works!
Also, curious what type of allergy the friend has, and what type of relief.
All of those are at least sometimes undesirable.
I suppose the biggest example of such a faustian weight-loss drug would be Fen-Phen, and it's issues were discovered within a few years of its rise to prominence.