The real question is how many UUIDs are generated per second around the world. This RFC suggests using them for automated processes, transactions, etc and generally seems to view them as an inexhaustible resource. If humanity collectively generates 1 trillion per second we can expect to see a 51% chance of collision in 8 months; if it's 100 billion it'd be 10 years, and if it's only 10 billion it'd be 100 years. I would expect even just one single computer with a modest GPU could get in the ballpark of these numbers if it wanted to just spawn UUIDs all day, let alone a huge server farm using them as part of some automated process.