Another thing that killed the amiga was it's lack of hackability and approachability. On the C64 you could start writing code right away, and instantly go into assembly with an extension
The Amiga, and none of the other 16-bit systems had an assembler built in either. They had interpreted BASICs just like the 8-bit systems, except on disk instead of in ROM.
a:\DEBUG < FOO.ASM
-a
(press enter until you reach the end of your source code at whatever address)
(enter a blank opcode to mark end of assembly range)
-g =100
voila, your (naturally, bug-free, right?) code assembles and runs.
It's living about as close to the land as you can get when it comes to an assembler, but it did the job.
from ms-dos 2.0 onwards debug was apparently re-entrant and could read its own binary from disk, "un"assemble it, assemble it again, and run another instance of itself from inside itself. When I first discovered this at 12 or so It felt I stumbled across a tiny doorway to some alternate dimension.