Pick 2 or three font sizes and cascade them.
Pick one serif and one san serif font.
Pick a base text color one accent color for your section headers.
Clearly separate your text from your visuals.
Use some bold within body text.
Break longer text up.
Shorten the entire resume to focus on only your best work, provide an appendix at the end for your full list.
I built a clear and simple adaptive resume I made a few years back here:
www.constantwanderer.com/resume