> cut the sample into around 5,000 slices — each just 34 nanometres thick — that could be imaged using electron microscopes.
Does anyone have any insight into how this is done without damaging the sample?
Does anyone have any insight into how this is done without damaging the sample?
It's also the tome as in book, more properly one volume of a multi-volume (or multi-part) set, though it now generally simply means any large book.
Paper: https://www.biorxiv.org/content/10.1101/2021.05.29.446289v4 See Figure 1.
The ATUM is described in more detail here https://www.eden-instruments.com/en/ex-situ-equipments/rmc-e...
and there's a bunch of nice photos and explanations here https://www.wormatlas.org/EMmethods/ATUM.htm
TL;DR this project is reaping all the benefits of the 21st century.