You are conflating the harms of the delivery mechanism with the harms of the substance.
Nicotine gum is relatively harmless for example. Or perhaps imbibe on a Nicotini[0]?
Nicotine gum is relatively harmless for example. Or perhaps imbibe on a Nicotini[0]?
[edit] Seems that nicotine is not really harmless, even in gum or patches: double the risk of heart palpitations and chest pains, 1.67 the risk of nausea and vomiting, 1.5 times the risk of gastrointestinal complaints, and 1.4 times the risk of insomnia.
Of course, if you measure anything this closely with >100k participants in RCTs, it's bound to have a significant effect. But these odds ratios are not exactly small.