Maybe given even 1,000,000 of observable universes the odds were just 1 out of 1,000,000.
How can people confidently claim that there must be some other civilizations, we wouldn't know the odds in the first place unless we know the exact mechanisms involved.
To me it seems like the probability could have been anything. It could have required any amount of certain chemical reactions to happen in certain order where the probability can vary wildly depending on the amount and likelihood of those reactions. E.g. it could be 0.01 to the power of 1,000,000 or as well as to the power of 10e64 and so on.