https://www.luminaprobiotic.com/
I'm temped to try it. But I'm waiting for others to review it first.
> There is no publicly available info about Lumina (street address, phone, financing, key personnel, facilities, etc.)
> Lumina is headquartered in Próspera, on the tourist island of Roatán in Honduras, South America. While the city is known for crypto, it is not known for the high tech pharmacological manufacturing and expertise that BCS3-L1 would require.
> Próspera is not subject to Honduran laws, taxes, (or FDA), because it was, for practical purposes, sold to billionaire Peter Theil and his investors . Because of a sketchy area of international law, Theil, et al, are able to sue (and are suing) Honduras for wanting to get out of the bad deal Honduras made with him. I.e., there could be resultant production issues for companies in Próspera. (Look up "ZEDE" and "Investor-State Dispute Settlement" if you're up for a major rabbit hole.)
excerpts from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232036/:
The recommended dose for dental caries prevention is 6–10 g/d....
Xylitol reduces the levels of mutans streptococci (MS) in plaque and saliva by disrupting their energy production processes, leading to futile energy cycle and cell death. It reduces the adhesion of these microorganisms to the teeth surface and also reduces their acid production potential.
...Thus, xylitol inhibits S. mutans growth essentially by starving the bacteria. Xylitol can inhibit the growth of harmful oral bacteria such as S. mutans, but its benefits do not stop in the oral cavity. Xylitol alcohol has been shown to impact growth of nasopharyngeal bacteria such as S. pneumonia and S. mitis, and hence has a role to play in nasopharyngeal pneumonia.
Xylitol decreases the incidence of dental caries by increasing salivary flow and pH and reducing the number of cariogenic (MS) and periodontopathic (Helicobacter pylori) bacteria, plaque levels, xerostomia, gingival inflammation, and erosion of teeth.
The predominant modality for xylitol delivery has been chewing gum. Chewing gum accelerates the processes of rinsing away acid and uptake of beneficial calcium phosphate molecules to remineralize tooth enamel. The recommended length of time for chewing after eating is approximately 20 minutes.
Consumption of xylitol chewing gum for ≥3 weeks leads to both long-term and short-term reduction in salivary and plaque S. mutans levels. A decrease in caries incidence has been reported among children exposed to the daily use of xylitol for 12–40 months. The long-term benefits have been observed up to 5 years after cessation of xylitol use. A prospective controlled, double-blind clinical trial confirmed that MS levels in plaque decreased as exposure to xylitol increased. However, a plateau effect was observed between 6.88 g/d and 10.32 g/d. The caries preventive effect was observed to be long term in relation to the teeth erupting during the period of xylitol use.You can get the same feeling from a Coke.
But eat good apples—Envy, Braeburn, Pink Lady, or at least a Royal Gala. Toss the Red Deliciouses into the bin.
A lightweight "conflict of interest notice" brushing off the concerns and providing plausible deniability ("Well, I did tell you"),
the company unironically described as "mostly rationalists",
gems like "if you eat a normal Western diet, your mouth microbiome is already pretty far from the design specs, and it’s unclear if using Lumina makes things worse."
"So probably this isn’t a risk for some kind of weird pandemic"
Q: "If you wanted to get rid of it, could you? A: Some kind of extreme course of oral antibiotics that nukes everything growing in your mouth would probably eradicate BCS3-L1, but this hasn’t been tested and would have side effects".