In the past in nearly all prior discussions on this the greatest proponents for Web Assembly were developers who wanted to bring their technologies into the browser because they hate JavaScript. That is a horrible business case that is more effort than any value returned and no user will ever care about.
Worse, it won't ever work if you intended it to be a JavaScript replacement because it cannot integrate into the interaction of the surrounding page, because it is a sandbox without compromise. This line of wishful thinking instills false hope and just pisses off everyone else, which slows adoption among other languages. The Web Assembly effort has been very clear about this from the very beginning, but people believe what they want to believe even after this has been clarified dozens of times.
There are absolutely valid business cases behind Web Assembly though, here are some:
* circumventing iphone restrictions
* desktop application portability
* security
* partial docker alternative
* promoting adoption and access of applications written lesser popular languages