I'm not sure if this still current, but a few years ago I switched from LibreOffice to MS Office because Calc was unbearably slow. I wasn't doing anything crazy, but also not trivial: 6 or 7 sheets, with a bunch of formulas with never more than about 500 cells filled (10 columns, 50 lines), and on most sheets a lot less.
Excel blazes through it. I feel it was a very good decision, even though I'm a miser.