I don't send marketing, I only send transactional emails. Notifications are opt-in, and transactional. Logins / signups are done via sending a TOTP to the email, these too are transactional.
If someone marks notifications of new posts in a subscribed thread as spam... fine, but this is self-solving, as this person will trigger no more email ever reaching them for that email address, meaning they also cannot now sign in to the website, and therefore cannot subscribe to more email updates, or visit things to refresh "last viewed", and so would never be notified again.
Emailing a TOTP as a login has increased deliverability by self-selecting the removal of those who hit the spam button. Deliverability of email from the webforums is over 99%.
Reporting email as spam, effectively bans oneself from the website. I didn't even need to do anything.