With that said, I think if anyone comes up with a "killer-app" for crypto, then it'll be on the Ethereum chain. They seem to be the only ones who consistently work towards adding capabilities to the core technology.
Edit: I realize I haven't commented on the article at all. This sentence stood out to me:
> Today, we have all the tools we'll need, and indeed most of the tools we'll ever have, to build applications that are simultaneously cypherpunk and user-friendly. And so we should go out and do it.
Clearly, this is an important step. But the two examples he provides as a beacon of what's possible (Daimo and Farcaster) don't inspire a lot of enthusiasm. Daimo is just a decentralized version of Venmo and Farcaster is a protocol to build social networks on the blockchain, which is yet another tool and not an application.
I do still like reading Vitaliks thoughts. He's a pretty good writer, and it's evident that he spends a lot of time actually thinking about the topics he writes about.