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Comment by freitzkriesler2 | Hacker News Reader

Another daily chemical that has estrogenic effects.

Guys (and maybe girls), get a full blood panel done that shows you the exact numbers of lipid, testosterone , and estrogen in your body.

I got panels done and was blown away by how low my T levels were (talking less than 250 ng/dl, full blown hypogonadism). My lipid panels show I had high ldl cholesterol and my blood pressure was high.

Worse yet, I work out 5 times a week, run, and eat a very healthy diet. I have a very healthy weight.

I've started taking 100ml shots split out twice a week. Over the past 6 weeks my pre and post blood works are startling.

LDL dropped considerably. My blood pressure dropped and is nowich safer.

It's death by a thousand cuts with all of these chemicals out there that turn friggin frogs gay poisoning us.

(Alex Jones ref btw)

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The following is not intended as advice for you, because I don't want to make assumptions about your healthcare situation (and you didn't ask me for advice). However I'm sharing it here in case it's helpful to others in whom you may have aroused curiosity.

Exogenous testosterone supplementation induces potentially permanent primary hypogonadism in patients that don't already have it. It can also eventually more or less completely atrophy the testes. Those effects can be partially counteracted by additional drugs, cycling, and so on, but those approaches have their own problems.

Some doctors want to go straight to testosterone supplementation, but I would insist on first eliminating secondary hypogonadism as a cause of low serum testosterone. See a good urologist or endocrinologist who will work with you to figure out root cause to the extent possible. There are treatments for secondary hypogonadism that will restore testosterone to very high levels in individuals with healthy testes.

Yes this is a concern of mine which is why I am dosing 100IU of HCG as a preventative to this.

> It's death by a thousand cuts with all of these chemicals out there that turn friggin frogs gay poisoning us.

I hope that statement is a joke and just reference to that insane Alex Jones clip. But if it's not, no amount of estrogenic compounds will turn you gay. Otherwise MTF folks would be universally straight after taking hormone therapy.

I don't think the term "gay" is particularly well defined for amphibians. Frogs do change sex though[1]. Whether or not exposure to exogenous estrogenic compounds triggers that I do not know.

[1] https://www.nationalgeographic.com/animals/article/frogs-rev...

Reference to Alex Jones.

>Guys (and maybe girls), get a full blood panel done that shows you the exact numbers of lipid, testosterone , and estrogen in your body.

It's probably just as much of a concern for females as for males. The idea of "estrogen" as "the female hormone" is a significant oversimplification.

Meh. I had he same blood work results as a 35 year old 4 years ago. I was "healthy" and exercising every day and eating "healthy".

Turns out running 8 miles every day and not eating over 100g of protein and not having enough fat KILLS your hormones because you're always in a catabolic state.

Now I only lift heavy, fixed my macros, get better sleep, focus on muscle mass, and DON'T need TRT. My natural T levels tripled in only 2 years.

Some biased ideas of "healthy" are not optimal.

Can you expand a bit? Seems very interesting...

How do you manage to keep 100g of protein daily?

What is fixing macros?

How do you know you were in catabolic state, were you constantly loosing weight?

> I've started taking 100ml shots split out twice a week

mind sharing what kind of shots?

Gonna be testosterone, and 100mg

I haven't ever seen a reputable study that proves a significant connection between T levels and sexual orientation in humans

There are no conclusive studies, but there are credible hypotheses and studies in animal models that suggest sexual orientation and gender identity (as well as other neurological factors) may be impacted by prenatal exposure to hormones and endocrine disruptors.

The science is a long way from having conclusive evidence either way, but there is a reasonable basis to think that it might have an impact, which should urge caution. If we found a new material that looked a lot like asbestos under a microscope, you'd presumably limit your exposure to it until proven safe?

Yes, prenantal exposure to hormones is one thing but I was specifically referring to GP's frankly controversial implicit claim that gay men possess lower T.

Anyway if I recall correctly that research suggests that higher prenantal T exposure increases likelihood of homosexuality, the opposite of what stereotypes might suggest

Its the opposite of what you may think. High T makes you more sexual and less inhibited. Many, many, many, many people turn to the dark side after using anabolic steroids. Even if they don't become full Sith masters, they often still like to dabble in dark side of Thailand.

Can you define what you consider a "very healthy diet"?

Breakfast is a protein shake of casein and collagen protein. With added berries in water. Oatmeal and a glass of coffee.

Lunch is a can of cooked chicken breast, 2 cups of fat free Greek yogurt , and a small salad with olive oil and vinegar.

Dinner is typically whatever my wife decides to make. She's Greek so a lot of Greek and Mediterranean food. Salads at every meal.

Try to drink coffee away from meals, caffeine & tannins in coffee interfere with minerals, protein and lipid absorption. The same applies to tea.

https://pubmed.ncbi.nlm.nih.gov/8360789/

https://pubmed.ncbi.nlm.nih.gov/6402915/

https://www.sciencedirect.com/science/article/pii/S000291652...

Will you have to stay on the shots forever or are you doing things in conjunction to stay at good levels (if so, what? Sounds like your lifestyle was already healthy)

To reap the benefits of TRT yes, but switching off means I just return to baseline.

With regular TRT shots, I've heard that there is a possibility that the baseline will lower due to changes in the HPG axis, leading to decreased production of LH and FSH, which leads to less testosterone being signaled to be naturally produced.

Taking extregenious testosterone disables your natural production. If you want to fire it back up you'll need to take hcg or clomid as post cycle therapy.

When on TRT, the naturally produced stuff is for all intents and purposes useless because you will be shooting up plenty that any extra will probably aromatise into estrogen anyway.

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