There's an extremely simple solution here. Just comply with the EU regulation in good faith. Sure, you lose some revenue that you'd otherwise get, but only for extremely popular games/apps like Fortnite etc, but your overall margins remain very thick. The vast majority of users would keep using only the App Store and vast majority of developers would publish there, so what's the big deal?
Instead it seems that what Apple is afraid of, is that this would lead to a chink in their armor, _eventually_ leading to their no-compromise attitude being re-evaluated in other markets as well, both by users (just a couple of TikToks from high-profile influencers would be enough to bring this issue into a more public light) and regulation bodies.