There's a custom 8-bit quantization (SFP), it's what we recommend. At 16 bit, we do bfloat16 instead of fp16 thanks to https://github.com/google/highway, even on CPU. Other quants - stay tuned.
python wrapper - if you want to run the model in python I feel like there's already a lot of more mature options available (see the model variations at https://www.kaggle.com/models/google/gemma) , but if people really want this and have something they want to do with a python wrapper that can't be done with existing options let me know. (similar thoughts wrt to API servers).