With CUDA you get a lot of flexibility which you don't get with Grayskull, at the expense of having a more layered/patched API which has been evolving for many years while R&D came up with new solutions to new problems.
I wonder what Nvidia's capabilities are in creating new, highly optimized cards, similar to Grayskull, but I wouldn't be surprised if they don't have any interest in creating them since their current products are already consuming all their resources.
It's great to see that companies like Tenstorrent are offering more optimized and pricewise more accessible products. It would also ease the situation with how hard it is to get Nvidia cards, because even companies doing only inferencing are buying chips which are developed to be able to do much more than that.