> No, immuno isn't always a second line treatment.

"for the vast majority of clinical trials" is what I said

> No you don't need to have failed other treatments before being added to a clinical trial

That wasn't my experience when looking for trials for my mom's metastatic cancer, but I hope you're right.

> No if you got colitis from immuno, chemo won't "reset" it, but strong doses of steroids might.

Two things can be true at once. I didn't say it's curative (neither are steroids), but chemo drugs can be given for severe uncontrolled autoimmune disease, because they are immunosuppressive.

> We discontinued my immuno before I got to that point

Too bad, I studied it for several years and my mom was a specialist on the adaptive immune system.