Attacks on US bases in the region have become a routine. Expect more casualties in the following months and years.
The US does not has a good response to this escalation. It could continue to bomb proxies, but it has almost no effect and it may even be counter-productive since it plays right into the Iranian propaganda, especially in the light of the Gaza war. Meanwhile, a big war with Iran would be a VERY risky endeavor with extremely unpredictable consequences for the global economy.