Mine can, and still might, it just *fingers crossed* has not happened yet and hopefully never will. However, I do have many of signs that have a high correlation with such outcomes. =(
The cancer is not my concern. For my disease in particular, the research, from what I have read, seems to believe that biologics do not increase the rate of cancer more than what the AI disease already does. Some studies have shown that there might even be a decrease in cancer once inflammation is controlled.
With that being said, it's the other potential side-effects like new incidents of Demyelinating diseases, Lupus-Like Reactions, seizures, liver damage, heart failure, etc..
The biologics seem to be getting safer with each iteration, and I would feel more comfortable on something like Skyrizi than Humira or Enbrel, but still not comfortable enough to pull the trigger.
Back story:
8 years ago, I had a minor sore throat and flu-like symptoms for about three days, then I was back up an running. Less than two weeks later, I was diagnosed with an autoimmune disorder. Thus, I am quite hesitant to open the doors for more infections. As the saying goes, "You can't put shit back in the horse."