Wine does run Windows music software quite well, sometimes even better than Windows; in fact the first and most famous hardware VST host, the Muse Receptor, used Linux + WINE under the hood almost 20 years ago.

Here's a SOS review from 2005: https://www.soundonsound.com/reviews/muse-research-receptor

I'm not so sure about that under Android, however, since latency in audio apps has been a big problem on that platform for ages.

Wine on Linux desktop runs an older version of Reason okish, I believe. I never tested that, just read somewhere. But if you wanna run, say, Reason 12, I don't think it works very well.

Sounds very fun (except latency), contrary to my sibling commenters I'd also prefer "big boy" music software (even if very old) to something "made for mobile".

Makes me think this could also be the way to run PureData (the whole thing, not just compiled patches) on Android. Was a bit surprised it never got ported last time I looked.

But... why??? Are you going to hook up a mouse and keyboard and USB midi controller? Why not just do that on a similarly priced laptop?