An aversion to using something beyond the stdlib for no good reason probably. Personally I've seen people reach for pandas only to accidentally coerce data in non-obvious ways. Clearly it depends on what you're planning on doing with the data afterwards though.

    import csv
    with open(filename, 'r') as f:
        r = csv.reader(f)
        for row in r:
            tsc, _, pc, *_ = row
            print(int(tsc, 16), int(pc, 16))