Statistics is a tricky thing. There are 43K traffic fatalities in the US per year and 53K deaths from colorectal cancer. Which means chances of dying from colorectal cancer is higher than dying in a traffic accident. Well, over a lifetime, but distribution over age can be different etc. In the same way 43K fatalities are not an even distribution over region, type of driving, destination, age etc.

Of course I have to admit that flying commercial airlines is safer by average numbers, in the US and for now. But if we estimate total flying hours as 1.3B/year (http://web.mit.edu/airlinedata/www/2018%2012%20Month%20Docum... times 100 passengers per aircraft) it only takes 1300 deaths per year to make it even with average traffic fatalities. If that flight had been unlucky enough to go down we would have had 177 deaths, already not "orders of magnitude safer" than driving. And the trend is not good.

But again, we are comparing apples to oranges. Driving is a very different experience, both long and short trips. Nobody chooses to drive from Boston to LA just out of fear of flying (well, maybe there are exceptions, but "nobody" is still a very accurate word). As for short trips, changes of getting into an accident in urban area driving to the airport is probably higher than driving in the other direction towards your destination. Again, it depends.