It's part joke and part telling people "hey, this stuff is really dangerous, take it seriously or you'll lose an eye, or both". I don't think I've seen a single lab with high-powered lasers that didn't have a variant of this sign.
A similar popular sign for chemical labs is "Carol Never Wore Her Safety Goggles. Now She Doesn't Need Them", depicting a blind woman with sunglasses and a white cane. (https://knowyourmeme.com/memes/carols-safety-goggles)
At least in my mind when I encounter something oddly said/written my mind starts suggesting contexts and I can clearly "see" myself going blind by doing me like things.
It's a very well worded warning, that spread because it's effective. The official warning saying that you must take precautions even if you don't see anything wrong just doesn't work well.