I work on a team that does BYO devices. Some have arm/mac, but most are on amd64/other. This forced us to make our development environment cross arch, even though our production environment is amd64/Linux only.

Some challenges included Docker images being arch specific, old Terraform modules lacking ARM support (forcing an upgrade we'd otherwise defer), and reduction in tooling we'd consider for production. We generally worry about arch specific bugs, although I don't believe we've seen any (other than complete failure to run certain tools).

Mostly x86 virtual machines for Linux and Windows. ARM ports of both platforms exist but don’t always meet use cases (binary apps, etc).

Kind of a edge case, but we were attempting to migrate from Docker to Podman, and found running x86 container images in Podman Desktop on M-series Macs to be unacceptably slow. Docker Desktop supports Rosetta 2 virtualization which performs fine, but Podman Desktop does not.

PSA: Dont get a mac with apple silicon if you need/want Virtual Box https://www.virtualbox.org/wiki/Downloads