[flagged]
The size of the pages side effects were written on says absolutely nothing about what the side effects are or their severity.
> Then there are the long term consequences, many studies keep coming out with surprises (recent buzzword “Ribosomal frameshift”
Ribosomal frameshift is in itself not a “long term consequence.” It is simply that depending on where translational of a piece of mRNA starts, different proteins can be produced. This is an essential part of how our own (or any other organism’s mRNA) is translated into proteins. other proteins present in a cell can regulate which proteins can be produced - again an essential part of how our cells function. This has been known about for decades.
It is one of the main potential areas that could lead to side effects of an mRNA vaccine so understanding what other proteins might be translated and under what circumstances is important.
Please don’t fear monger without any actual evidence to back it.
> other proteins present in a cell can regulate which proteins can be produced - again an essential part of how our cells function
I thought manipulating this was a design goal.
Regardless, I somewhat doubt the simple story presented to the public is 100% accurate.
Naive question: Do they say what the side effects are and their severity in an easily accessible manner somewhere?
5 WARNINGS AND PRECAUTIONS
5.1 Management of Acute Allergic Reactions
Appropriate medical treatment to manage immediate allergic reactions must be immediately available in the event an acute anaphylactic reaction occurs following administration of Moderna COVID-19 Vaccine.
Monitor Moderna COVID-19 Vaccine recipients for the occurrence of immediate adverse reactions according to the Centers for Disease Control and Prevention (CDC) guidelines (https://www.cdc.gov/vaccines/covid-19/clinical-consideration...).
5.2 Myocarditis and Pericarditis
Postmarketing data with authorized or approved mRNA COVID-19 vaccines demonstrate increased risks of myocarditis and pericarditis, particularly within the first week following vaccination. For Moderna COVID-19 Vaccine, the observed risk is highest in males 18 years through 24 years of age. Although some cases required intensive care support, available data from short-term follow-up suggest that most individuals have had resolution of symptoms with conservative management. Information is not yet available about potential long-term sequelae.
The CDC has published considerations related to myocarditis and pericarditis after vaccination, including for vaccination of individuals with a history of myocarditis or pericarditis (https://www.cdc.gov/vaccines/covid-19/clinical-consideration...).
5.3 Syncope
Syncope (fainting) may occur in association with administration of injectable vaccines. Procedures should be in place to avoid injury from fainting.
5.4 Altered Immunocompetence
Immunocompromised persons, including individuals receiving immunosuppressive therapy, may have a diminished response to Moderna COVID-19 Vaccine.
5.5 Limitations of Vaccine Effectiveness
Moderna COVID-19 Vaccine may not protect all vaccine recipients.
Because there are people we know it doesn't work for and people we don't know it doesn't work for.
“Similarly, researchers in California observed no major differences between vaccinated and unvaccinated individuals in terms of SARS-CoV-2 viral loads in the nasopharynx, even in those with proven asymptomatic infection.
Thus, the current evidence suggests that current mandatory vaccination policies might need to be reconsidered, and that vaccination status should not replace mitigation practices such as mask wearing, physical distancing, and contact-tracing investigations, even within highly vaccinated populations.”
https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
A whole bunch of OTC drugs carry CYA lists like this, it's not the gotcha you think it is.
> but to me as a healthy 40yo person, with no known immunity issues, not overweight etc.
My father is getting a stent put in for a 70% artery blockage. Older of course but skinny, looks after his health, exercises. He had no symptoms like pain or being out of breath. Just high cholesterol.
A friend of mine in his early 30's healthy nearly got taken out by RSV last year because it aggravated a heart condition he was unaware of.
People aren't as healthy as they like to convince themselves they are.
Comorbidities run amok, known and unknown.
It's an interesting take. From what we know so far, the risk from taking vaccine is much smaller than from covid infection. You might counter this with highlighting the "so far" part, but keep in mind that many studies keep coming out with surprises not only regarding vaccine side effects, but also negative long term effects of covid.
And that's even assuming it's effective in the first place. The "it reduces symptoms" mantra is gaslighting since the whole point of its accelerated approval and forced application was for the reduction of transmission.
While this is anecdotal, the amount of people I know personally that have told me they had significant health issues with a Covid vaccine or covid booster is weird.
Since at the same time mass vaccination rolled out, essentially all lockdowns were lifted and at least speaking for myself, that is when I caught Covid (and got sick in general again, no colds for almost two years was nice).
Does that matter if you get covid anyway?
Without the vaccine, your body has to create those antibodies while you are already sick, and that takes time. This gives the virus a huge head start.
We're not just talking the flu-like symptoms here, the most relevant symptoms are "risk of death decreased."
Otherwise for Coronavirus vaccines you couldn't argue that risks are much smaller for any given person under any given conditions. E.g. a person could be completely isolated for the next 10 years and have virtually 0% chance of getting Covid-19, so in this case there's no calculation that could show a vaccine being with more favourable benefits/risks.
If there's a 1/10,000 chance of giving you a sore shoulder that would be worse in the calculations if you are for sure to be isolated from being anywhere near the virus.
Well yes, in completely absurd and unrealistic situation the risk of taking vaccine might be larger than that of Covid-19.
What about a person living in simple solitude who works remotely and orders everything in? This is a realistic, non-absurd scenario and they would possibly risk getting Covid-19 on their way to the appointment of getting the vaccine.
The biggest whine from anti-vaxers was that they were being told they needed a vaccine to do social things they enjoyed , like air travel or coughing on the elderly.
I don't think you're hypothetical neo-hermit would being doing either of these, so itseems unlikely they'll be "forced" to get a vaccine.
None the less doesn't mean that calculations show that to every one.
Whatever "anti-vaxers" think doesn't change the calculations.
On the group level you would have to consider the damage on the group level as well from not getting vaccinated due to increase of covid-19 spread, and increased hospitalisation levels.
On the global communication and messaging level I agree you should tell everyone to vaccinate as you can't easily provide everyone with those calculators. And not to mention people not being able to come up with correct values for those factors themselves.
1. Age. Not all age groups were recommended the vaccine.
2. Last time or where you have had Covid-19 at all.
3. General pattern of activity and the amount of contacts with other people.
4. Last time you have had the vaccine.
E.g. in my country through it's technical systems didn't allow you to get a Covid-19 vaccine when you had the virus within last 6 months. While US recommended the vaccine much shorter period of time after having had Covid-19.
> Almost no one is actually living as a hermit
Also consider that in 2021, there were actually many people living as hermits, including I, as I really didn't want to get the virus. At the time I was terrified of getting it. In 2020-2021, I did live with my partner, but we worked remotely, worked out outside away from other people and we did cardio/gym, but with home made equipment or outside keeping distance to other people.
I think it was quite common in 2021.
Isolation doesn't mean lack of sun exposure.
Medical checkups would depend on the age and healthiness of the person.
Although I would agree that 10 years later in your life is unlikely to create an issue.
> The Andaman and Nicobar Islands Protection of Aboriginal Tribes Regulation 1956[9] prohibits travel to the island, and any approach closer than 5 nautical miles (9.3 km), in order to protect the remaining tribal community from "mainland" infectious diseases against which they likely have no acquired immunity. The area is patrolled by the Indian Navy.[10]
A: What behaviors or environments lead to adult immune systems calibrated to minimize autoimmune dysfunctions.
B: Comparing populations that already/ haven't developed inherited countermeasures against certain diseases.
C: (In some cases) Specific pathogens where it is less-damaging to encounter them at different phases of life.
In particular, I'd point out that sometimes a population strong against a particular disease does not necessarily have "better" immune systems... Sometimes it's literally survivorship bias, where all of the vulnerable individuals they used to have already died in tragic ways.
There are no side effects observed from mRNA CV vaccines that could be worse when compared to cancers with 1%+ mortality rate.
As a reminder you won't be taking it before the cancer, you would be taking it after the fact.
This might be true if the treatment was thousands of times more effective than the best available alternative treatment. I don't know enough about this treatment to know if that's the case or not
And there were even fewer such effects when the vaccines have rolled out back in 2020 with emergency approval, but without being used “in production” beforehand.
Now we know much more about the mRNA platform, but I still can’t exclude the possibility entirely for me. So I will take my chances and focus much more on quality of food, on staying fit, reducing stress etc. etc.
For example rabies vaccines is not given to everyone, however after you get rabies you will be given that vaccine.
Vaccine in this case is a less harmful training tool to prepare you for the more harmful pathogen that may still be reaching its peak strength.
You can think of vaccines as a training tool. In some cases it might provide you with a response that can completely throw the pathogen out, in other cases it will just be able to fight it better.
If you could spread something as bad as rabies by sneezing. You would see actual mandatory vaccinations, not the mild nudge people have been complaining about the last three years.
What are those?
But they are all very general and very vague. Eat right. Exercise. Avoiding smoking and alcohol, unless it's red wine. Be wealthy Drink Coffee.
Sorry just when I see people suggesting healthy lifestyle under this and other articles for things like heart disease mRNA treatments, it generally betrays that they view being sick as a personal failing.
1 in 2 people will contract cancer according to the NHS. https://www.nhs.uk/conditions/cancer/
The biggest factor with cancer is age. https://www.cancerresearchuk.org/health-professional/cancer-...
Projecting further into the future, the world is going to be divided into those with access to and willingness to use biotechnology and those who don’t. Note that I am including things like fitness and health tracking apps under the umbrella of biotech.
I saved this post as a favorite and set up a reminder in 2 years and in 5 years about it. Hope there will be nothing to add, and we just got ourselves a mighty vaccines platform at zero long term consequences.