I lived in SF for ~10ish years up until 2020 and still return regularly for work/friends.
I agree that it is mostly downtown that is dead but the rest of your comment seems hyperbolic to me. Hayes Valley, Valencia, Polk was way more lively when I was there.
> best job market
The hundreds in SF laid off this year may disagree
> most lucrative
yes, incomes and stocks do generally increase yoy. Tautology.
> and most advanced
as does technology