I tried Mixtral via ollama on my Apple M1 Max with 32GB of RAM, and was a total nonstarter. I ended up having to powercycle my machine. I then just used two L4 GPU's on Google Cloud (so 48GB of GPU RAM, see [1]) and it was very smooth and fast there.
[1] https://github.com/sagemathinc/cocalc-howto/blob/main/ollama...