Alaska, Hawaii, Vermont, and Maine all do not allow for billboard advertisement, so at least there are a few places you can go for respite.
I don't know if that's the rule for all roads, or just for interstates. I don't know if it's for driver safety if they veer off the road, or for avoiding distraction, or just to limit advertising. But I like it.
I haven't worked out exactly why some exist, but almost none do. The law is here:
https://law.lis.virginia.gov/vacode/title33.2/chapter12/
Regardless, the general feel of driving here is very different from many other states because of this rule. It's one of the first things I notice when I drive somewhere else in the US.